A review on medical plants affecting Staphylococcus aureus

Document Type: Review Article

Authors

Shahid Chamran University of Ahvaz

Abstract

Background and aims: Infectious diseases are among the most important causes of mortality around the world and according to the WHO report 10.5 million cases of death were happened due to infections. Staphylococcus aureus is one of the most important pathogen that its infections are varied from local infections to life threatening infections. With regard to high antibiotic resistance of this agent its control and treatment is a challenge in medicine. The aim of this study was to review the effective medicinal plants against S. aureus with special attention of native plants of Iran.
Methods: A comprehensive literature review was performed on papers that have been published from 2004 till 2016 in data resources such as NCBI, Sciencedirect, Springer, Web of science and as well as local databases such as Irandoc, Islamic science citation (ISC) and magiran with special focus on those that have been reported native medicinal plants in Iran. The selected keywords were Staphylococcus aureus, medicinal plant, natural antibiotic, antibacterial plant and medicinal herbs.
Results: Different studies were found that have reported effective medicinal plants against S. aureus and were able to significantly inhibit bacterial growth. As well as different parts of these plants have been investigated for antibacterial activity and found that considerable differences are present among these parts of plants.
Conclusion: Based on the reported studies, there are different medicinal plants in Iran that can be regarded as effective source for discovery new antibacterial agents against 
S. aureus and treatment of resistant strains.

Keywords

Main Subjects


1. Moghadam MS, Maleki S, Darabpour E, Motamedi H, Nejad SMS. Antibacterial activity of eight Iranian plant extracts against methicillin and cefixime restistant Staphylococcus aureus strains. Asian Pac J Trop Dis. 2010; 3(4): 262-5.

2. Ding W, Gu J, Cao L, Li N, Ding G, Wang Z, et al. Traditional Chinese herbs as chemical resource library for drug discovery of anti-infective and anti-inflammatory. J Ethnopharmacol. 2014; 155(1): 589-98.

3. Harbarth S, Fankhauser C, Schrenzel J, Christenson J, Gervaz P, Bandiera-Clerc C, 
et al. Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. Jama. 2008; 299(10): 
1149-57.

4. Salari Sharif A, Sattari M, Moradi M, Shahrokhabad R. Detection of Staphylococcus aureus Entrotoxin Genes A and B in Clinical Samples of the Patients Referring to the Medical Centers of Kerman and Rafsanjan Cities by PCR Technique. J Rafsanjan Univ Med Sci. 2012; 11(2): 
128-36.

5. Foster TJ. The Staphylococcus aureus “superbug”. J Clin Invest. 2004; 114(12): 1693-6.

6. Rasmussen RV, Fowler VG, Skov R, Bruun NE. Future challenges and treatment of Staphylococcus aureus bacteremia with emphasis on MRSA. Future Microbiol. 2011; 6(1): 43-56.

7. Seyyednejad S, Motamedi H. A review on native medicinal plants in Khuzestan, Iran with antibacterial properties. Int J Pharmacol. 2010; 6(5): 551-60.

8. Motamedi H, Darabpour E, Gholipour M, Seyyednejad S. Antibacterial effect of ethanolic and methanolic extracts of Plantago ovata and Oliveria decumbens endemic in Iran against some pathogenic bacteria. Int J Pharmacol. 2010; 6(2): 117-22.

9. Darabi N, Habibollahi H, Shahbabian K. Molecular Epidemiology of Staphylococcus aureus Isolated from patients and personnel in Army hospital. James. 2010; 8(3): 193-9.

10. Warnke PH, Lott AJ, Sherry E, Wiltfang J, Podschun R. The ongoing battle against multi-resistant strains: In vitro inhibition of hospital-acquired MRSA, VRE, Pseudomonas, ESBL E. coli and Klebsiella species in the presence of plant-derived antiseptic oils. J Craniomaxillofac Surg. 2013; 41(4): 321-6.

11. Darabpour E, Motamedi H, Poshtkouhian Bavi A, Nejad S, Mansour S. Antibacterial activity of different parts of Peganum harmala L. growing in Iran against multi-drug resistant bacteria. Excli J. 2011; 10: 252-63.

12. Darabpour E, Motamedi H, Nejad SMS. Antimicrobial properties of Teucrium polium against some clinical pathogens. Asian Pac J Trop Med. 2010; 3(2): 124-7.

13. Seyyednejad S, Maleki S, Damabi NM, Motamedi H. Antibacterial activity of Prunus mahaleb and Parsley (Petroselinum crispum) against some pathogen. Asian J Biol Sci. 2008; 1: 51-5.

14. Koochak H, Seyyednejad S, Motamedi H. A preliminary study on the antibacterial activity of Euphorbia granulata forssk against some pathogens. J Ethnophar. 2010; 1: 1-3.

15. Seyyednejad SM, Koochak H, Darabpour E, Motamedi H. A survey on Hibiscus rosa-sinensisAlcea rosea L. and Malva neglecta Wallr as antibacterial agents. Asian Pac J Trop Med. 2010; 3(5): 351-5.

16. Uprety Y, Asselin H, Dhakal A, Julien N. Traditional use of medicinal plants in the boreal forest of Canada: review and perspectives. J Ethnobiol Ethnomed. 2012; 8: 7.

17. Seyydnejad SM, Niknejad M, Darabpoor I, Motamedi H. Antibacterial activity of hydroalcoholic extract of Callistemon citrinus and Albizia lebbeck. Am J Appl Sci. 2010; 7(1): 13-16.

18. Motamedi H, Seyyednejad M, Dehghani F, Hasannejad Z. Investigation of antibacterial activity of ethanolic and methanolic extracts of Mentha pulegium L. Zahedan J Res Med Sci. 2014; 16(10): 55-9.

19. Maleki S, Seyyednejad SM, Damabi NM, Motamedi H. Antibacterial activity of the fruits of Iranian Torilis leptophylla against some clinical pathogens. Pak J Biol Sci. 2008; 11(9): 1286-9.

20. Koochak H, Seyyednejad SM, Motamedi H. Preliminary study on the antibacterial activity of some medicinal plants of Khuzestan (Iran). Asian Pac J Trop Med. 2010; 3(3): 180-4.

21. Seyyednejad SM, Motamedi H, Najvani FD, Hassannejad Z. Antibacterial effect of Eucalyptus microtheca. Int J Enteric Pathog. 2014; 2(2): e16515.

22. Safari E, Amiri M, Bahador A, Amiri M, Esmaeili D. The study of antibacterial effects of alcoholic extracts of Arum maculatum, Allium hirtifolium and Teucrium polium against nosocomial resistance bacteria. Int J Curr Microbiol App Sci. 2014; 3(2): 601-5.

23. Motamedi H, Alivand S, Ebrahimian M, Moosavian S. The antibacterial properties of methanolic extract of Teucrium polium against MRSA. J Kermanshah Univ Med Sci. 2015; 18(10): 557-62.

24. Ur-rahman M, Ul-haq Hafeez I, 
Gul Sh, Ali kayani S. Antibacterial effects of Zatoria multiflora Boiss extract on community acquired methicillin resistant Staphylococcus aureus. Adv Biol Res. 2007; 1(5-6): 141-5.

25. Zuo GY, An J, Han J, Zhang YL, Wang GC, Hao XY, et al. Isojacareubin from the Chinese herb Hypericum japonicum: Potent antibacterial and synergistic effects on clinical methicillin-resistant Staphylococcus aureus (MRSA). Int J Mol Sci. 2012; 13(7): 8210-8.

26. Abouzeed YM, Elfahem A, Zgheel F, Ahmed MO. Antibacterial in vitro activities of selected medicinal plants against methicillin resistant Staphylococcus aureus from Libyan environment. J Environ Anal Toxicol. 2013; 3: 194.

27. Snowden R, Harrington H, Morrill K, Jeane L, Garrity J, Orian M, et al. A comparison of the anti-Staphylococcus aureus activity of extracts from commonly used medicinal plants. J Altern Complement Med. 2014; 20(5): 375-82.

28. Buru AS, Pichika MR, Neela V, Mohandas K. In vitro antibacterial effects of Cinnamomum extracts on common bacteria found in wound infections with emphasis on methicillin-resistant Staphylococcus aureus. J Ethnopharmacol. 2014; 153(3): 587-95.

29. Fensterseifer IC, Silva ON, Malik U, Ravipati AS, Novaes NR, Miranda PR, et al. Effects of cyclotides against cutaneous infections caused by Staphylococcus aureus. Peptides. 2015; 63: 38-42.

30. Kaur S, Kaur HP, Aggarwal S. Evaluation of antibacterial activity, antioxidant potential and phytochemicals of Withania sominifera. World J Pharm Pharm Sci. 2015; 4(3): 1032-42.