Study of phytochemical characteristics Artemisia persica Boiss in Ilam Province

Document Type: Original Article

Authors

1 Professor in Agronomy Dept., Ramin University of Agriculture and Natural Resources, Ahwaz, I.R. Iran

2 Msc. Agronomy and Iran nanotechnology laboratory network chromatography Experts Workgroup , Ramin University of Agriculture and Natural Resources, Ahwaz, I.R. Iran

Abstract

Background and aims: The genus Artemisia is one of the largest and most widely distributed of the nearly 100 genera in the tribe Anthemideae of the Asteraceae (Compositae). 34 species of Artemisia have been reported in Iran. Several secondary metabolites characterize the chemical composition of the genus Artemisia. Therefore, the current study aimed to phytochemical Characteristics of Artemisia persica Boiss collected from the Farm and natural habitat of Ilam.
Methods: The aerial parts of plants were collected from Farm and Kabirkooh mountain. After extraction of Artemisinin, the analysis was performed with an HPLC system. Extraction of essential oil it was done by hydro distilled. Phytocomponents identified in Artemisia persica Boiss essential oils by GC/MS system.
Results: The essential oil yield was reported in Kabirkooh mountain and Farm 0.92 % and 0.6%, respectively. The major oil compounds of samples of Artemisia persica Boiss collected were included: α-Pinene, 1,8-Cineole, (Z)-Sabinene hydrate, (E)-Pinocarveol, Pinocarvone, Artedouglasia oxide C, Laciniata furanone E, Artedouglasia oxide D, Artedouglasia oxide B. The Artemisinin was 2.7 ppm in the Kabirkooh mountain sample. However the Farm sample had 1.5 ppm.
Conclusions: To achieve the appropriate level of the target compounds it is important to considered an appropriate place for sampling.

Keywords

Main Subjects


1. Mucciarelli M, Maffei M. 2002. Introduction to the genus Artemisia. In: Wright C. W. (ed.), Artemisia.-Taylor and Francis, pp.1-50.

2. Mozaffarian V. 2008: Anthemidae and Echinopeae in Assadi et al. Flora of Iran, no 59. –Research Institute of Forests and Rangelands, Tehran.

3. Lopes-Lutz D, Alviano DS, Alviano CS, Kolodziejczyk PP. 2008. Screening of chemical composition, antimicrobial and antioxidant activities of Artemisia essential oils. Phytochem, 69(8):1732-1738.

4. Rustaiyan A,  Faridchehr A. 2014. A Review on constituents and biological activities of further Iranian Artimisia species. Int J Pharmaceutical, Bio. Chem. Sci, 3(3):6-14.

5. Rabie M, Asri Y, Hamzehee B, Jalili A. Sefidkon F. 2012. Determination of chemotaxonomic indices

of Artemisia sieberi Besser based on environmental parameters in Iran. Iran J Bot, 18 (1): 149-157.

6. Sefidkon F, Tayefeh Hendi E, Fakhari F. Teimouri M. 2013. Essential oil composition and antimicrobial activities of oil and alcoholic extract of Artemisia spicigera C. Koch. from Mazandaran province. Eco-phytochem J Med P, 1 (2): 1-13.

7. Arab HA, Rahbari S, Rassouli A, Moslemi MH, Khosravirad F. 2006. Determination of artemisinin in Artemisia sieberi and anticoccidial effects of the plant extract in broiler chickens. Trop Anim Health Prod, 38(6):497-503.

8. Efferth T, Dunstan H, Sauerbrey A, Miyachi H. Chitambar CR. 2001. The an timalarial artesunate is also active against cancer. Int J Oncol, 18: 767-773.

9. Lai H, Singh NP. 2006. Oral artemisinin prevents and delays the development of 7,12dimethylbenz[a]anthracene (DMBA)-induced breast cancer in the rat. Cancer Letters, 231: 43-48.

10. Romero MR, Serrano MA, Vallejo M, Efferth T, Alvarez M, Marin JJ. 2006. Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the Bovine Viral Diarrhoea Virus (BVDV). Planta Med, 72: 1169-1174.

11. Mojarrab M, Delazar A, Esnaashari S, Heshmati Afshar F. 2012. Chemical composition and general toxicity of essential oils extracted from the aerial parts of Artemisia armeniaca Lam. and A. incana L. Druce growing in Iran. Res Pharm Sci,8:65-69.

12. Hao JY, Han W , Huang SD, Xue BY, Deng X. 2002. Microwave-assisted extraction of artemisinin from Artemisia annua L. Sep. Purific. Technol, 28:191-196.

13. Erdemoglu N, Orhan L, Kartal M, Adıgüzel N, Bani B. 2007. Determination of Artemisinin in Selected Artemisia L. Species of Turkey by Reversed Phase HPLC.Rec. Nat. Prod. 1(3) :36-43.

14. Adams RP. 2001. Identification of essential oils components by gas chromatography/ quadruple mass spectroscopy. Allured Publishing Corp, Carol Stream, IL. 456p.

15. Bicchi C, Frattini C, Sacco T. 1985. Essential Oils of Three Asiatic Artemisia Species. Phytochem, 24: 2440-2442.

16. Sadeghpour O, Asghari G. Shams MR. 2004. Composition of essential oil of Artemisia persica Boiss. Iran J Pharm Res, 3: 65-67.

17. Mirjalili BF, Hakimi Meybody MH, Mazloum Ardakani M, Rustaiyan AH, Ameri N, Masoudi S. Bamoniri A. 2006. Chemical composition of the essential oil from aerial parts, leaves, flowers and roots of Artemisia persica Boiss. from Iran. J Essential Oil Res, 18(5): 544-547.

18. Mahbubi M, Feyzabadi M, Haghi G, Hoseini H. 2007. Studying of antimicrobial properties and chemical compound in Oliveria decumbens vent essence.  Iran J Med Aro P, 1(24): 56-65.

19. Palevitch D. 1987.  Recent advances in the cultivation of medicinal plants. Acta Hortic , 208: 29-34.

20. Kostova I, Dinchev D. 2005. Saponins in Tribulus terrestris-chemistry and bioactivity. Phytochem Rev, 4(2): 111-37.